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Product Description
– Colistin (Polymyxin E) is an orally active polypeptide antibiotic. Colistin has excellent activity against various Gram-negative rod-shaped bacteria, including multidrug-resistant Pseudomonas aeruginosa, Acinetobacter baumannii and Klebsiella pneumoniae. Colistin is associated with nephrotoxicity. Colistin can be used for the research of infections caused by Gram-negative bacilli[1][2].
Web ID
– HY-113678
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C53H100N16O13 (for E1)
References
– [1]Silpak Biswas, et al. Colistin: an update on the antibiotic of the 21st century. Expert Rev Anti Infect Ther. 2012 Aug;10(8):917-34. |[2]Jian Li, et al. Pharmacokinetics of colistin methanesulphonate and colistin in rats following an intravenous dose of colistin methanesulphonate. |[3]Michael T Eadon, et al. Cell cycle arrest in a model of colistin nephrotoxicity. Physiol Genomics. 2013 Oct 1;45(19):877-88.
CAS Number
– 1066-17-7
Molecular Weight
– 1169.50
SMILES
– [Colistin]
Clinical Information
– Launched
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Antibiotic;Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
