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Product Description
– Coleon-U-quinone is a potent P-gp inhibitor. Coleon-U-quinone can inhibit cancer cells viability and sensitize multidrug resistance cancer cells to Doxorubicin (HY-15142A)[1].
Web ID
– HY-N10563
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H24O5
References
– [1]Ntungwe EN, et al. C20-nor-Abietane and Three Abietane Diterpenoids from Plectranthus mutabilis Leaves as P-Glycoprotein Modulators. ACS Med Chem Lett. 2022 Mar 11;13(4):674-680.
CAS Number
– 65714-83-2
Molecular Weight
– 344.40
SMILES
– O=C(C1=C2[C@@](CCCC3(C)C)(C3=C(C1=O)O)C)C(C(C)C)=C(O)C2=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– P-glycoprotein
Pathway
– Membrane Transporter/Ion Channel
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
