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COH34 analog 1
SKU
HY-115666-10 mg
Category Reference compound
Tags Cancer, Cell Cycle/DNA Damage, Poly(ADP-ribose) Glycohydrolase (PARG)
$85 – $720
Products Details
Product Description
– COH34 analog 1, a metabolite, is an oxidized analog of COH34. COH34 is a potent poly(ADP-ribose) glycohydrolase (PARG) inhibitor[1].
Web ID
– HY-115666
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C18H15NO3S
References
– [1]Chen SH, et al. Targeting dePARylation selectively suppresses DNA repair-defective and PARP inhibitor-resistant malignancies. Sci Adv. 2019 Apr 10;5(4):eaav4340.
CAS Number
– 314248-24-3
Molecular Weight
– 325.38
Compound Purity
– 98.75
SMILES
– O=S(C1=CC=C(C)C=C1)(/N=C/C2=C3C=CC=CC3=CC=C2O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Poly(ADP-ribose) Glycohydrolase (PARG)
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.