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Coenzyme FO
$450 – $3,850
Products Details
Product Description
– Coenzyme FO, a deazaflavin chromophore, acts as an important hydride acceptor/donor in the central methanogenic pathway[1][2].
Web ID
– HY-136497
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C16H17N3O7
References
– [1]Purwantini E, et al. Conversion of NO2 to NO by reduced coenzyme F420 protects mycobacteria from nitrosative damage. Proc Natl Acad Sci U S A. 2009;106(15):6333‐6338.|[2]Mills DJ, et al. De novo modeling of the F(420)-reducing [NiFe]-hydrogenase from a methanogenic archaeon by cryo-electron microscopy. Elife. 2013;2:e00218. Published 2013 Mar 5.|[3]de Poorter LMI, et al. Hydrogen concentrations in methane-forming cells probed by the ratios of reduced and oxidized coenzyme F420. Microbiology. 2005;151(Pt 5):1697‐1705.|[4]Philmus B, et al. Biosynthetic versatility and coordinated action of 5′-deoxyadenosyl radicals in deazaflavin biosynthesis. J Am Chem Soc. 2015;137(16):5406-5413.
CAS Number
– 37333-48-5
Molecular Weight
– 363.32
Compound Purity
– 99.06
SMILES
– O[C@H]([C@H](O)[C@H](O)CO)CN(C1=CC(O)=CC=C1C=C2C(N3)=O)C2=NC3=O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– DMSO : 5 mg/mL (ultrasonic)|Ethanol : < 1 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Bacterial;Endogenous Metabolite
Pathway
– Anti-infection;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
