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Product Description
– Cnicin is a sesquiterpene lactone. Cnicin has antiproliferative effects, and induces cell death in primary myeloma cells. Cnicin also has anti-SARS-CoV-2 activity. Cnicin inhibits viral replication of SARS CoV-2 with an IC50 of 1.18 μg/mL[1].
Web ID
– HY-137984
Shipping
– Room temperature
Molecular Formula
– C20H26O7
References
Р[1]Alhadrami HA, et al. Cnicin as an Anti-SARS-CoV-2: An Integrated In Silico and In Vitro Approach for the Rapid Identification of Potential COVID-19 Therapeutics. Antibiotics (Basel). 2021 May 7;10(5):542.|[2]J̦hrer K, et al. Antimyeloma activity of the sesquiterpene lactone cnicin: impact on Pim-2 kinase as a novel therapeutic target. J Mol Med (Berl). 2012 Jun;90(6):681-93.
CAS Number
– 24394-09-0
Molecular Weight
– 378.42
SMILES
– O=C(C([C@@H](O)CO)=C)O[C@@H](C/C(C)=C/CC1)[C@](C2=C)([H])[C@@](OC2=O)([H])/C=C1CO
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– SARS-CoV
Pathway
– Anti-infection
Product type
– Reference compound
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