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CMP-Sialic acid (sodium salt)
SKU
HY-112942A-1 mg
Category Reference compound
Tags Endogenous Metabolite, Metabolic Disease, Metabolic Enzyme/Protease
$55 – $576
Products Details
Product Description
– CMP-Sialic acid (CMP-Neu5Ac) sodium salt is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. CMP-Sialic acid sodium salt provides a substrate for Golgi sialyltransferases. CMP-Sialic acid sodium salt is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates[1].
Web ID
– HY-112942A
Storage Temperature
– -80°C
Shipping
– Dry Ice
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C20H30N4NaO16P
References
– [1]Münster AK, et al. Mammalian cytidine 5′-monophosphate N-acetylneuraminic acid synthetase: a nuclear protein with evolutionarily conserved structural motifs. Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9140-5.|[2]Jing Song, et al. Reassembled Biosynthetic Pathway for a Large-scale Synthesis of CMP-Neu5Ac. Mar Drugs. 2003 Dec; 1(4): 34-45.|[3]Mercado CP, et al. A serotonin-induced N-glycan switch regulates platelet aggregation. Sci Rep. 2013 Sep 30;3:2795.
CAS Number
– 1007117-62-5
Molecular Weight
– 636.43
Compound Purity
– 92.51
SMILES
– O[C@@H]1[C@H](O[C@@H](N2C(N=C(N)C=C2)=O)[C@@H]1O)COP(O[C@@]3(O[C@@]([C@H](NC(C)=O)[C@@H](O)C3)([H])[C@H](O)[C@H](O)CO)C(O)=O)(O[Na])=O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– H2O : 125 mg/mL (ultrasonic)
Target
– Endogenous Metabolite
Isoform
– Human Endogenous Metabolite
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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