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Products Details
Product Description
– CM572 is a selective irreversible partial sigma-2 receptor agonist. CM572 has antitumor activity. CM572 induces dose-dependent cell death, with an EC50 of 7.6 μM in SK-N-SH neuroblastoma cells. CM572 can be used for the research of kinds of diseases such as neuroblastoma, breast cancer[1].
Web ID
– HY-122112
Shipping
– Room temperature
Molecular Formula
– C22H23FN4O2S
References
– [1]Nicholson H, et al. Characterization of CM572, a Selective Irreversible Partial Agonist of the Sigma-2 Receptor with Antitumor Activity. J Pharmacol Exp Ther. 2015 Aug;354(2):203-12.
CAS Number
– 1121932-91-9
Molecular Weight
– 426.51
SMILES
– O=C1OC2=CC(N=C=S)=CC=C2N1CCCCN3CCN(CC3)C4=CC=C(C=C4)F
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Sigma Receptor
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
