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CM572
Products Details
Product Description
– CM572 is a selective irreversible partial sigma-2 receptor agonist. CM572 has antitumor activity. CM572 induces dose-dependent cell death, with an EC50 of 7.6 μM in SK-N-SH neuroblastoma cells. CM572 can be used for the research of kinds of diseases such as neuroblastoma, breast cancer[1].
Web ID
– HY-122112
Shipping
– Room temperature
Molecular Formula
– C22H23FN4O2S
References
– [1]Nicholson H, et al. Characterization of CM572, a Selective Irreversible Partial Agonist of the Sigma-2 Receptor with Antitumor Activity. J Pharmacol Exp Ther. 2015 Aug;354(2):203-12.
CAS Number
– 1121932-91-9
Molecular Weight
– 426.51
SMILES
– O=C1OC2=CC(N=C=S)=CC=C2N1CCCCN3CCN(CC3)C4=CC=C(C=C4)F
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Sigma Receptor
Pathway
– Neuronal Signaling
Product type
– Reference compound
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