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Clopidogrel thiolactone
$360 – $1,080
Products Details
Product Description
– Clopidogrel thiolactone is an active metabolites containing thiols resulting from thionolactone transformation of clopidogrel (HY-15283). Clopidogrel thiolactone is a P2Y12 receptor inhibitor, is a potent antiplatelet agent[1][2].
Web ID
– HY-15876
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C16H16ClNO3S
References
– [1]Shan J, et, al. Overcoming clopidogrel resistance: discovery of vicagrel as a highly potent and orally bioavailable antiplatelet agent. J Med Chem. 2012 Apr 12;55(7):3342-52.|[2]Hagihara K, et, al. Comparison of formation of thiolactones and active metabolites of prasugrel and clopidogrel in rats and dogs. Xenobiotica. 2009 Mar;39(3):218-26.
CAS Number
– 1147350-75-1
Molecular Weight
– 337.82
Compound Purity
– 98.0
SMILES
– O=C(OC)[C@@H](N1CCC(S2)C(C1)=CC2=O)C3=C(Cl)C=CC=C3
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– DMSO : 50 mg/mL (ultrasonic)|Ethanol : 5 mg/mL (ultrasonic;warming;heat to 40°C)
Target
– P2Y Receptor
Isoform
– P2Y12 Receptor
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
