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Clonidine-d4
Products Details
Product Description
– Clonidine-d4 is the deuterium labeled Clonidine. Clonidine hydrochloride is an agonist of α2-adrenoceptor and potent antihypertensive agent[1][2][3][4][5].
Web ID
– HY-B0409S
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C9H5D4Cl2N3
References
– [1]Bugajski J, et al. The involvement of central alpha-adrenergic and histamine H2-receptors in the hypothermia induced by clonidine in the rat. Neuropharmacology. 1980 Jan;19(1):9-15.;Zhang YM, et al. Clonidine induces calcitonin gene-related peptide expres|[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
CAS Number
– 62497-68-1
Molecular Weight
– 234.12
SMILES
– ClC(C=CC=C1Cl)=C1NC2=NC([2H])([2H])C([2H])([2H])N2
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease; Endocrinology; Cancer
Solubility
– 10 mM in DMSO
Target
– Adrenergic Receptor;Isotope-Labeled Compounds
Pathway
– GPCR/G Protein;Neuronal Signaling;Others
Product type
– Isotope-Labeled Compounds
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