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Clocinnamox (mesylate)
SKU
HY-101306-2mg
Category Reference compound
Tags GPCR/G Protein;Neuronal Signaling, Neurological Disease, Opioid Receptor
$502
Only 1000 item(s) left in stock.
Products Details
Product Description
– Clocinnamox (mesylate) is a potent opioid antagonist acting at mu, kappa and delta-receptors. Clocinnamox is a selective mu-receptor antagonist than kappa and delta-receptors[1].
Web ID
– HY-101306
Shipping
– Room temperature
Molecular Formula
– C30H33ClN2O7S
References
– [1]S D Comer, et, al. Clocinnamox: a novel, systemically-active, irreversible opioid antagonist. J Pharmacol Exp Ther. 1992, 262, 3.|[2]E R Butelman, et, al. Clocinnamox antagonism of opioid suppression of schedule-controlled responding in rhesus monkeys. Psychopharmacology (Berl). 1996, 123, 4.
CAS Number
– 117332-69-1
Molecular Weight
– 601.11
SMILES
– OC1=C(O2)C([C@]([C@@H]2C(CC3)=O)(CCN4CC5CC5)[C@]3(NC(/C=C/C6=CC=C(Cl)C=C6)=O)[C@H]4C7)=C7C=C1.CS(=O)(O)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Opioid Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
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