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Clobetasone butyrate

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Products Details

Product Description

– Clobetasone butyrate is a synthetic glucocorticoid and has topical anti-inflammatory activity especially in skin. Clobetasone butyrate can be used to relieve corticosteroid-responsive dermatoses, including atopic dermatitis and psoriasis[1].

Web ID

– HY-B1616

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C26H32ClFO5

References

– [1]Munro DD, et al. Clobetasone butyrate, a new topical corticosteroid: clinical activity and effects on pituitary-adrenal axis function and model of epidermal atrophy.|[2]Michael Stewart, et al. Clobetasone butyrate for inflammatory skin conditions.

CAS Number

– 25122-57-0

Molecular Weight

– 478.98

Compound Purity

– 99.24

SMILES

– C[C@@]1(C2)[C@](C(CCl)=O)(OC(CCC)=O)[C@@H](C)C[C@@]1([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3(F)C2=O)=O

Clinical Information

– Launched

Research Area

– Inflammation/Immunology

Solubility

– DMSO : ≥ 250 mg/mL

Target

– Glucocorticoid Receptor

Pathway

– Immunology/Inflammation;Vitamin D Related/Nuclear Receptor

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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