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Products Details
Product Description
– Clezutoclax is a potent payload and also a Bcl-XL inhibitor. Clezutoclax can be used in the synthesis of antibody-drug conjugates (ADCs)[1].
Web ID
– HY-137774
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C83H102N12O24S2
References
– [1]Boni V, et al. The Resurgence of Antibody Drug Conjugates in Cancer Therapeutics: Novel Targets and Payloads. Am Soc Clin Oncol Educ Book. 2020 Mar;40:1-17.
CAS Number
– 1949843-71-3
Molecular Weight
– 1715.89
SMILES
– O=C(OCC(C=CC(NC([C@H](C)NC([C@H](C(C)C)NC(CN(C1=O)[C@@H](C[C@@H]1N(C2=O)C(C=C2)=O)COCC[S](=O)(O)=O)=O)=O)=O)=C3)=C3CC[C@@H]([C@@H]([C@H]4O)O)O[C@@H]([C@H]4O)C(O)=O)N(CC[C@H](O)CO)CCO[C@](C5)(C6)C[C@@](C[C@@]6(C7)C)(C[C@]57C)CN8C(C)=C(C(C=CC(N(CCC9=CC=C%10)CC9=C%10C(NC%11=NC%12=CC=CC=C%12S%11)=O)=N%13)=C%13C(O)=O)C=N8
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Cytotoxin;Bcl-2 Family
Pathway
– Antibody-drug Conjugate/ADC Related;Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
