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Products Details
Product Description
– Clathrin-IN-4 (compound 8b), a Wiskostatin (HY-12534) analogue, is a potent inhibitor of clathrin mediated endocytosis with an IC50 of 2.1 μM. Clathrin-IN-4 is a dynamin I GTPase activity inhibitor with an IC50 of 9.1 μM[1].
Web ID
– HY-152218
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C17H18Br2N2O
References
– [1]Peter J Cossar, et al. Wiskostatin and other carbazole scaffolds as off target inhibitors of dynamin I GTPase activity and endocytosis. Eur J Med Chem. 2022 Dec 15;247:115001.
CAS Number
– 762242-59-1
Molecular Weight
– 426.15
SMILES
– CN(C[C@H](CN1C2=CC=C(C=C2C3=CC(Br)=CC=C31)Br)O)C
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Dynamin
Pathway
– Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
