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Clanfenur
SKU
HY-106825-Get quote
Category Reference compound
Tags Cancer, Cell Cycle/DNA Damage;Cytoskeleton, Microtubule/Tubulin
Products Details
Product Description
– Clanfenur is a substituted benzoylphenylurea, an analogue of the pesticide fenfluramide, with potential antineoplastic activity. Clanfenur can bind to the colchicine-binding site on β-tubulin, inhibit microtubule polymerization, and thus prevent tumor cell replication[1].
Web ID
– HY-106825
Shipping
– Room temperature
Molecular Formula
– C16H15ClFN3O2
References
– [1]J D Jonkman-de Vries, et al. Pharmaceutical development of a parenteral formulation of the investigational anticancer drug clanfenur. PDA J Pharm Sci Technol. 1997 Mar-Apr;51(2):89-95.Â
CAS Number
– 51213-99-1
Molecular Weight
– 335.76
SMILES
– ClC(C=C1)=CC=C1NC(NC(C2=C(C=CC=C2F)N(C)C)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Microtubule/Tubulin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
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