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Claficapavir

SKU HY-145560-10 mg Category Tags , ,

$130$1,200

Products Details

Product Description

– Claficapavir (A1752) is a specific nucleocapsid protein (NC) inhibitor with an IC50 around 1 μM. Claficapavir strongly binds the HIV-1 NC (Kd=20 nM) thereby inhibiting the chaperone properties of NC and leading to good antiviral activity against the HIV-1[1].

Web ID

– HY-145560

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– COVID-19-anti-virus

Molecular Formula

– C17H12ClNO4S2

References

– [1]Kim MJ, et al. Identification and characterization of a new type of inhibitor against the human immunodeficiency virus type-1 nucleocapsid protein. Retrovirology. 2015;12:90. Published 2015 Nov 6.

CAS Number

– 2055732-24-4

Molecular Weight

– 393.86

Compound Purity

– 99.14

SMILES

– O=C(N(C(S/1)=S)CCC(O)=O)C1=CC2=CC=C(C3=CC=C(C=C3)Cl)O2

Clinical Information

– No Development Reported

Research Area

– Infection

Solubility

– DMSO : 200 mg/mL (ultrasonic;warming;heat to 40°C)

Target

– HIV

Isoform

– HIV-1

Pathway

– Anti-infection

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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