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Products Details
Product Description
– CL2-MMT-SN38 is a SN-38 derivative. SN-38, an anticancer agent, is an active metabolite of the Topoisomerase I inhibitor Irinotecan (CPT-11)[1].
Web ID
– HY-145513
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C102H122N12O24
References
– [1]Moon SJ, et al. Antibody conjugates of 7-ethyl-10-hydroxycamptothecin (SN-38) for targeted cancer chemotherapy. J Med Chem. 2008;51(21):6916-6926.
CAS Number
– 1084888-82-3
Molecular Weight
– 1900.13
SMILES
– O=C(C1CCC(CC1)CN2C(C=CC2=O)=O)NCC(N=N3)=CN3CCOCCOCCOCCOCCOCCOCCOCCOCCNC(COCC(N[C@@H](CC4=CC=CC=C4)C(N[C@H](C(NC5=CC=C(C=C5)COC(O[C@]6(C7=C(COC6=O)C(N8C(C(C(C8)=C(C9=C%10)CC)=NC9=CC=C%10O)=C7)=O)CC)=O)=O)CCCCNC(C%11=CC=CC=C%11)(C%12=CC=CC=C%12)C%13=CC=C(C=C%13)OC)=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Topoisomerase
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
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