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CK2 inhibitor 3
SKU
HY-143461-Get quote
Category Reference compound
Tags Cancer, Casein Kinase, Cell Cycle/DNA Damage;Stem Cell/Wnt
Products Details
Product Description
– CK2 inhibitor 3 is a potent CK2 inhibitor with IC50 value of 280 nM. CK2 inhibitor 3 inhibits endocellular CK2, significantly affects viability of tumour cells and shows remarkable selectivity on a panel of 320 kinases[1].
Web ID
– HY-143461
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C13H9BrN4O3S
References
– [1]Dalle Vedove A, Zonta F, Zanforlin E, et al. A novel class of selective CK2 inhibitors targeting its open hinge conformation. Eur J Med Chem. 2020;195:112267.
Molecular Weight
– 381.20
SMILES
– COC1=CC(/C=C(C(NC2=NN=C(S2)Br)=O)C#N)=CC=C1O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Casein Kinase
Isoform
– CK2
Pathway
– Cell Cycle/DNA Damage;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.