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Products Details
Product Description
– CK2-IN-3 is a selective and potent CK2 inhibitor (Kd: 12 nM), with IC50 values of 1.51 μM (CK2α) and 7.64 μM (CK2α’). CK2-IN-3 can be used in the research of cancers[1].
Web ID
– HY-151382
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C22H26N4O7
References
– [1]Andreas Krämer, et al. Optimization of pyrazolo[1,5-a]pyrimidines lead to the identification of a highly selective casein kinase 2 inhibitor. Eur J Med Chem. 2020 Dec 15;208:112770.
Molecular Weight
– 458.46
SMILES
– O=C(O)C1=CC=C(C2=C3N=C(N(C(OC(C)(C)C)=O)CCOCCO)C=CN3N=C2)C=C1O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Casein Kinase
Isoform
– CK2
Pathway
– Cell Cycle/DNA Damage;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
