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Product Description
– CK2α-IN-1 (compound 2) is a selective CK2α inhibitor (IC50=7.0 µM; Ki=1.6 µM) that exhibits a non-ATP-competitive mode of action. CK2α-IN-1 exhibits good potential for anticancer studies[1].
Web ID
– HY-148318
Shipping
– Room temperature
Molecular Formula
– C16H11N3O4S
References
– [1]Bestgen B, et al. 2-Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. 1. Identification of an Allosteric Binding Site. J Med Chem. 2019 Feb 28;62(4):1803-1816.
CAS Number
– 443747-52-2
Molecular Weight
– 341.34
SMILES
– O=C(C1=CC(NC2=NC(C3=CC([N+]([O-])=O)=CC=C3)=CS2)=CC=C1)O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Casein Kinase
Pathway
– Cell Cycle/DNA Damage;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
