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Products Details
Product Description
– cis,trans-Germacrone is a isomer of Germacrone (HY-N0440). Germacrone exhibits a wide range of antitumor, antioxidant and anti-inflammatory effects. Germacrone inhibits lung cancer cell proliferation and alters the Akt/MDM2/p53. Germacrone also arrests cell cycle at G1/S phase[1].
Web ID
– HY-145670
Shipping
– Room temperature
Molecular Formula
– C15H22O
References
– [1]Zhao Y, et al. Germacrone induces lung cancer cell apoptosis and cell cycle arrest via the Akt/MDM2/p53 signaling pathway. Mol Med Rep. 2021 Jun;23(6):452.
CAS Number
– 32663-51-7
Molecular Weight
– 218.33
SMILES
– C/C(C)=C1C(C/C(C)=CCC/C(C)=C/C1)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Akt;MDM-2/p53
Pathway
– Apoptosis;PI3K/Akt/mTOR
Product type
– Reference compound
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