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cis-ACCP
$283
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Products Details
Product Description
– cis-ACCP is an orally active antimetastatic matrix metalloproteinase-2 (MMP-2) selective inhibitor. cis-ACCP can inhibit MMP-2 and MMP-9 with IC50 values of 4 μM and 20 μM, respectively. cis-ACCP can be used for the research of a variety of chronic diseases[1].
Web ID
– HY-131417
Shipping
– Room temperature
Molecular Formula
– C7H15N2O4P
References
– [1]Hoffman, Amnon et al. Carbamoylphosphonate matrix metalloproteinase inhibitors 6: cis-2-aminocyclohexylcarbamoylphosphonic acid, a novel orally active antimetastatic matrix metalloproteinase-2 selective inhibitor–synthesis and pharmacodynamic and pharmacokinetic analysis. Journal of medicinal chemistry vol. 51,5 (2008): 1406-14.
CAS Number
– 777075-44-2
Molecular Weight
– 222.18
SMILES
– OP(O)(C(N[C@H]1[C@@H](N)CCCC1)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection; Inflammation/Immunology; Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– MMP
Isoform
– MMP-2;MMP-9
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
