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Products Details
Product Description
– Cimiside E (25-Anhydrocimigenol xyloside) is a triterpene xyloside, Cimiside E possesses apoptotic action on gastric cancer cells, with an IC50 value of 14.58 μM. Cimiside E induces cell cycle arrest at G2/M phase, and mediates apoptosis through the induction of the caspase cascade for both the extrinsic and intrinsic pathways[1][2].
Web ID
– HY-N10018
Shipping
– Room temperature
Molecular Formula
– C35H54O8
References
– [1]Guo LY, et al. Cimiside E arrests cell cycle and induces cell apoptosis in gastric cancer cells. Arch Pharm Res. 2009 Oct;32(10):1385-92. |[2]Jamróz MK, et al. One new and six known triterpene xylosides from Cimicifuga racemosa: FT-IR, Raman and NMR studies and DFT calculations. Spectrochim Acta A Mol Biomol Spectrosc. 2012 Jul;93:10-8.
CAS Number
– 154822-57-8
Molecular Weight
– 602.80
SMILES
– C[C@]12[C@@]3([H])[C@@]4(CC[C@@]1([C@]5([H])[C@@]6(O[C@]([C@@H](O6)C(C)=C)([H])C[C@H]5C)[C@@H]2O)C)[C@@]7([C@@](C(C)([C@H](CC7)O[C@H]8[C@@H]([C@H]([C@@H](CO8)O)O)O)C)([H])CC3)C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Caspase
Isoform
– Caspase 3
Pathway
– Apoptosis
Product type
– Natural Products
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