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Cimetidine sulfoxide
SKU
HY-136338-10 mg
Category Reference compound
Tags GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling, Histamine Receptor, Inflammation/Immunology
$154 – $480
Products Details
Product Description
– Cimetidine sulfoxide (Cimetidine sulphoxide) is a sulfoxide metabolite of Cimetidine. Cimetidine is a histamine H2-receptor antagonist. Cimetidine has the potential for peptic ulcer disease and upper gastrointestinal haemorrhage treatment[1].
Web ID
– HY-136338
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– C10H16N6OS
References
– [1] Larsson R, et al. The pharmacokinetics of cimetidine and its sulphoxide metabolite in patients with normal and impaired renal function. Br J Clin Pharmacol. 1982;13(2):163-170.|[2]HE Barber, et al. The Transport of Cimetidine Across the Rat Small Intestine in Vitro. B r J Pharmacol. 1979 Jul;66(3):496P-497P.|[3] Ryta A. Kuzel, et al. Investigations into the chirality of the metabolic sulfoxidation of cimetidine. Chirality (1994), 6(8), 607-14.
CAS Number
– 54237-72-8
Molecular Weight
– 268.34
Compound Purity
– 97.0
SMILES
– O=S(CC/N=C(NC)/NC#N)CC1=C(C)N=CN1
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 83.33 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Histamine Receptor
Pathway
– GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
Product type
– Reference compound
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