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Ciclopirox
$55 – $77
Products Details
Product Description
– Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic[1].
Web ID
– HY-B0450
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C12H17NO2
Citations
– Clin Transl Med. 2022 Aug;12(8):e999.|Eur J Pharmacol. 2022 Jul 19;175156.|Front Pharmacol. 2021 May 10;12:670224.|Pharmacol Res. 7 January 2022, 106046.
References
– [1]Niewerth, M., et al., Ciclopirox olamine treatment affects the expression pattern of Candida albicans genes encoding virulence factors, iron metabolism proteins, and drug resistance factors. Antimicrob Agents Chemother, 2003. 47(6): p. 1805-17.|[2]Leem, S.H., et al., The possible mechanism of action of ciclopirox olamine in the yeast Saccharomyces cerevisiae. Mol Cells, 2003. 15(1): p. 55-61.|[3]Ratnavel, R.C., R.A. Squire, and G.C. Boorman, Clinical efficacies of shampoos containing ciclopirox olamine (1.5%) and ketoconazole (2.0%) in the treatment of seborrhoeic dermatitis. J Dermatolog Treat, 2007. 18(2): p. 88-96.
CAS Number
– 29342-05-0
Molecular Weight
– 207.27
Compound Purity
– 99.84
SMILES
– CC(C=C(C1CCCCC1)N2O)=CC2=O
Clinical Information
– Launched
Research Area
– Infection; Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Autophagy;Bacterial;Ferroptosis;Fungal
Pathway
– Anti-infection;Apoptosis;Autophagy
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
