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Products Details
Product Description
– CHS-111 is a benzyl indazole inhibitor of superoxide anion O2- generation. CHS-111 inhibits the cell migration, and reduces the formyl-Met-Leu-Phe- but not phorbol ester-stimulated phospholipase D activity, with the IC50 of 3.9 μM[1].
Web ID
– HY-116730
Shipping
– Room temperature
Molecular Formula
– C21H18N2O
References
– [1]Chang LC, et al. Signaling mechanisms of inhibition of phospholipase D activation by CHS-111 in formyl peptide-stimulated neutrophils. Biochem Pharmacol. 2011;81(2):269-278.
CAS Number
– 886755-63-1
Molecular Weight
– 314.38
SMILES
– OCC1=CC=C(C=C1)C2=C3C=CC=CC3=NN2CC4=CC=CC=C4
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– Reactive Oxygen Species
Pathway
– Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Product type
– Reference compound
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