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Chromenone 1
$315
Only 1000 item(s) left in stock.
Products Details
Product Description
– Chromenone 1 is a potent osteogenic bone morphogenetic protein (BMP) potentiator. Chromenone 1 exhibits a unique mode of action as it induces a pronounced, kinase-independent, negative TGFβ feedback that enhances nuclear BMP-Smad signaling outputs[1].
Web ID
– HY-143891
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C18H10F3N3O2
References
– [1]Wesseler F, et al. Probing Embryonic Development Enables the Discovery of Unique Small-Molecule Bone Morphogenetic Protein Potentiators. J Med Chem. 2022;65(5):3978-3990.
CAS Number
– 1639929-29-5
Molecular Weight
– 357.29
SMILES
– O=C1C(C2=CC=C(C(F)(F)F)C=C2)=C(N3N=CN=C3)OC4=CC=CC=C14
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– TGF-β Receptor
Pathway
– TGF-beta/Smad
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
