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Products Details
Product Description
– Chrexanthomycin C is an orally active marine natural product with remarkable bioactivities. Chrexanthomycin C has binding affinity for DNA (G4C2)4 G4 with a Kd value of 2.8 mM. Chrexanthomycin C can be used for the research of neurodegenerative disease such as amyotrophic lateral sclerosis (ALS)[1].
Web ID
– HY-N10579
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C31H24O15
References
– [1]Aifang Cheng, et al. Selective C9orf72 G-Quadruplex-Binding Small Molecules Ameliorate Pathological Signatures of ALS/FTD Models. Journal of Medicinal Chemistry Article ASAP.
Molecular Weight
– 636.51
SMILES
– CC(CC(C=C1CCC(C(O)=C(O2)C(C(C3=C2C(O[C@H](O4)[C@H](O)[C@@H](O)C(O)=C4C(O)=O)=CC=C3)=O)=C5O)=C5C1=C6O)=C6C(O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– DNA/RNA Synthesis
Pathway
– Cell Cycle/DNA Damage
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
