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Products Details
Product Description
– Cholicamideβ (compound 6) is a self-assembling, small molecule, cancer vaccine adjuvant. Cholicamideβ can form virus-like particles with low cytotoxicity. Cholicamideβ, upon binding to peptide antigens, enhances antigen presentation by dendritic cells and induces antigen-specific T cells. Cholicamideβ can induce apoptosis and necrosis[1].
Web ID
– HY-156087
Shipping
– Room temperature
Molecular Formula
– C55H94N2O6
References
– [1]Zhuo SH, et al. Identification of a Self-Assembling Small-Molecule Cancer Vaccine Adjuvant with an Improved Toxicity Profile. J Med Chem. 2023 Sep 7.. .
Molecular Weight
– 879.34
SMILES
– [H][C@]12C[C@@H]([C@@]3([C@H](CC[C@]3([C@]1([H])CC[C@@]4(C[C@@H](CC[C@]24C)O)[H])[H])[C@@H](CCC(NCCCCCCCNC(CC[C@H]([C@@H]5[C@@]6(C)[C@@H](O)C[C@@]7([H])[C@@](CC[C@@]8(C[C@@H](CC[C@@]87C)O)[H])([C@@]6(CC5)[H])[H])C)=O)=O)C)C)O
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Necroptosis
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
