Chloroquinoxaline sulfonamide

$165$1,680

Products Details

Product Description

– Chloroquinoxaline sulfonamide (Chloroquinoxaline), a structural analogue of sulfaquinoxaline, is a topoisomerase II alpha/beta poison. Chloroquinoxaline sulfonamide is used to control coccidiosis in poultry, rabbit, sheep, and cattle[1]. Antitumor activity[2].

Web ID

– HY-106662

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C14H11ClN4O2S

References

– [1]Gao H, et al. Chloroquinoxaline sulfonamide (NSC 339004) is a topoisomerase IIalpha/beta poison. Cancer Res. 2000 Nov 1;60(21):5937-40.|[2]Branda RF, et al. Cellular pharmacology of chloroquinoxaline sulfonamide and a related compound in murine B16 melanoma cells. Biochem Pharmacol. 1988 Dec 1;37(23):4557-64.

CAS Number

– 97919-22-7

Molecular Weight

– 334.78

Compound Purity

– 99.06

SMILES

– ClC1=CC=CC2=NC(NS(=O)(C3=CC=C(N)C=C3)=O)=CN=C12

Clinical Information

– Phase 2

Research Area

– Cancer; Infection

Solubility

– DMSO : 125 mg/mL (ultrasonic)

Target

– Molecular Glues;Parasite;Topoisomerase

Isoform

– Coccidia;Topo II

Pathway

– Anti-infection;Cell Cycle/DNA Damage;PROTAC

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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