Download Files:
Chloroquinoxaline sulfonamide
$165 – $1,680
Products Details
Product Description
– Chloroquinoxaline sulfonamide (Chloroquinoxaline), a structural analogue of sulfaquinoxaline, is a topoisomerase II alpha/beta poison. Chloroquinoxaline sulfonamide is used to control coccidiosis in poultry, rabbit, sheep, and cattle[1]. Antitumor activity[2].
Web ID
– HY-106662
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C14H11ClN4O2S
References
– [1]Gao H, et al. Chloroquinoxaline sulfonamide (NSC 339004) is a topoisomerase IIalpha/beta poison. Cancer Res. 2000 Nov 1;60(21):5937-40.|[2]Branda RF, et al. Cellular pharmacology of chloroquinoxaline sulfonamide and a related compound in murine B16 melanoma cells. Biochem Pharmacol. 1988 Dec 1;37(23):4557-64.
CAS Number
– 97919-22-7
Molecular Weight
– 334.78
Compound Purity
– 99.06
SMILES
– ClC1=CC=CC2=NC(NS(=O)(C3=CC=C(N)C=C3)=O)=CN=C12
Clinical Information
– Phase 2
Research Area
– Cancer; Infection
Solubility
– DMSO : 125 mg/mL (ultrasonic)
Target
– Molecular Glues;Parasite;Topoisomerase
Isoform
– Coccidia;Topo II
Pathway
– Anti-infection;Cell Cycle/DNA Damage;PROTAC
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
