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Chloropyramine hydrochloride
SKU
HY-B1305-10mM/1mL
Category Reference compound
Tags Cancer; Endocrinology, FAK;Histamine Receptor;VEGFR, GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling;Protein Tyrosine Kinase/RTK
$60 – $66
Products Details
Product Description
– Chloropyramine hydrochloride is a histamine receptor H1 antagonist which can also inhibit the biochemical function of VEGFR-3 and FAK.
Web ID
– HY-B1305
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C16H21Cl2N3
References
– [1]Kurenova EV, et al. Small molecule chloropyramine hydrochloride (C4) targets the binding site of focal adhesion kinase and vascular endothelial growth factor receptor 3 and suppresses breast cancer growth in vivo. J Med Chem. 2009 Aug 13;52(15):4716-24.
CAS Number
– 6170-42-9
Molecular Weight
– 326.26
Compound Purity
– 99.73
SMILES
– CN(C)CCN(CC1=CC=C(Cl)C=C1)C2=NC=CC=C2.[H]Cl
Clinical Information
– Launched
Research Area
– Cancer; Endocrinology
Solubility
– DMSO : 30 mg/mL (ultrasonic;warming)|H2O : 100 mg/mL (ultrasonic)
Target
– FAK;Histamine Receptor;VEGFR
Isoform
– H1 Receptor;VEGFR3/Flt-4
Pathway
– GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.