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CHK1-IN-7
$648
Only 1000 item(s) left in stock.
Products Details
Product Description
– CHK1-IN-7 (Compound 10c) is a potent human CHK1 inhibitor. CHK1-IN-7 shows no single agent effect, potentiates the antiproliferative effect of Gemcitabine HY-17026 in both prostate and breast cancer cell lines. CHK1-IN-7 can be used for the research of cancer[1].
Web ID
– HY-103367
Shipping
– Room temperature
Molecular Formula
– C25H24N4O2
References
– [1]Teng M, et al. Structure-based design and synthesis of (5-arylamino-2H-pyrazol-3-yl)-biphenyl-2′,4′-diols as novel and potent human CHK1 inhibitors. J Med Chem. 2007 Nov 1;50(22):5253-6.
CAS Number
– 838823-31-7
Molecular Weight
– 412.48
SMILES
– OC1=CC(O)=CC=C1C2=CC=C(C3=NNC(NC4=CC=C(CNC5CC5)C=C4)=C3)C=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Checkpoint Kinase (Chk)
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
