Download Files:
Products Details
Product Description
– Chk1-IN-6 is a potent, selective, and orally bioavailable CHK1 inhibitor candidate.
Web ID
– HY-139901
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C16H18F3N7
References
– [1]Jin T, et al. Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile. J Med Chem. 2021 Oct 28;64(20):15069-15090.
CAS Number
– 2428423-77-0
Molecular Weight
– 365.36
SMILES
– N#CC(C=C1)=NC=C1NC2=NC=C(C(F)(F)F)C(NCCC(C)(C)N)=N2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Checkpoint Kinase (Chk)
Isoform
– Chk1
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
