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CHK1-IN-3
$315
Only 1000 item(s) left in stock.
Products Details
Product Description
– CHK1-IN-3 is a Checkpoint Kinase 1 (CHK1) inhibitor with an IC50 of 0.4 nM[1].
Web ID
– HY-128601
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C20H23N9O
References
– [1]Tong L, et al. Discovery of (R)-5-((5-(1-methyl-1H-pyrazol-4-yl)-4-(methylamino)pyrimidin-2-yl)amino)-3-(piperidin-3-yloxy)picolinonitrile, a novel CHK1 inhibitor for hematologic malignancies. Eur J Med Chem. 2019 Jul 1;173:44-62.
CAS Number
– 2097252-39-4
Molecular Weight
– 405.46
SMILES
– CNC1=C(C2=CN(C)N=C2)C=NC(NC3=CN=C(C#N)C(O[C@H]4CNCCC4)=C3)=N1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Checkpoint Kinase (Chk)
Isoform
– Chk1
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
