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Chitin synthase inhibitor 13
Products Details
Product Description
– Chitin synthase inhibitor 13 (compound 12g) is a non-competitive inhibitor of chitin synthase, with an IC50 of 106.7 μM. Chitin synthase inhibitor 13 exhibits a broad-spectrum of antifungal activity[1].
Web ID
– HY-155569
Shipping
– Room temperature
Molecular Formula
– C21H19N5O5S
References
– [1]Du C, et, al. Design, synthesis and biological evaluation of novel spiro-quinazolinone derivatives as chitin synthase inhibitors and antifungal agents. Eur J Med Chem. 2023 Jul 5;255:115388.
CAS Number
– 2925228-79-9
Molecular Weight
– 453.47
SMILES
– O=C(NC1=CC=C([N+]([O-])=O)C=C1)/C=C/C(NC2=CC3=C(NC4(CSCC4)NC3=O)C=C2)=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Fungal
Pathway
– Anti-infection
Product type
– Reference compound
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