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Products Details
Product Description
– Chicanine is a lignan compound of Schisandra chinesis, inhibits LPS-induced phosphorylation of p38 MAPK, ERK 1/2 and IκB-α, with anti-inflammatory activity[1].
Web ID
– HY-N2270
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C20H22O5
References
– [1]Chicanine, et al. Anti-inflammatory effects of chicanine on murine macrophage by down-regulating LPS-induced inflammatory cytokines in IκBα/MAPK/ERK signaling pathways. Eur J Pharmacol. 2014 Feb 5;724:168-74.
CAS Number
– 78919-28-5
Molecular Weight
– 342.39
SMILES
– OC1=CC=C([C@@H]2O[C@@H](C3=CC=C(OCO4)C4=C3)[C@H](C)[C@@H]2C)C=C1OC
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– ERK;IKK;p38 MAPK
Pathway
– MAPK/ERK Pathway;NF-κB;Stem Cell/Wnt
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
