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Products Details
Product Description
– Chevalone C, a meroterpenoid fungal metabolite, shows antimalarial activity with IC50 value of 25.00 μg/mL. Chevalone C has anti-proliferative activity on colon HCT116, liver HepG2 and melanoma A375 cancer cell lines[1][2].
Web ID
– HY-120607
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C28H40O5
References
– [1]Sasiphimol Sawadsitang, et al. Antimalarial and cytotoxic constituents of Xylaria cf. cubensis PK108. Nat Prod Res. 2015;29(21):2033-6.|[2]M Prata-Sena, et al. Cytotoxic activity of Secondary Metabolites from Marine-derived Fungus Neosartorya siamensis in Human Cancer Cells. Phytother Res. 2016 Nov;30(11):1862-1871.
CAS Number
– 1318025-77-2
Molecular Weight
– 456.61
SMILES
– CC(OC1=C2C[C@@]3([C@@](C)(O1)CC[C@]4([C@]3(CC[C@@]5([C@@]4(CC[C@@H](C5(C)C)OC(C)=O)C)[H])C)[H])[H])=CC2=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection
Solubility
– 10 mM in DMSO
Target
– Parasite
Isoform
– Plasmodium
Pathway
– Anti-infection
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
