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CGRP antagonist 1
$680 – $2,040
Products Details
Product Description
– CGRP antagonist 1 is a highly potent CGRP receptor antagonist with a Ki and IC50 of 35 and 57 nM, respectively.
Web ID
– HY-112262
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C29H26N4O4
References
– [1]Stump CA, et al. The discovery of highly potent CGRP receptor antagonists. Bioorg Med Chem Lett. 2009 Jan 1;19(1):214-7.
CAS Number
– 1123757-49-2
Molecular Weight
– 494.54
SMILES
– O=C(NC1=CC2=C(C[C@@]3(C4=CC=CN=C4NC3=O)C2)C=C1)CN5C(C6(CCOCC6)C7=C5C=CC=C7)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease; Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– CGRP Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
