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Ceftobiprole
$450 – $3,800
Products Details
Product Description
– Ceftobiprole (Ro 63-9141) is a broad-spectrum cephalosporin with high levels of in vitro activity against methicillin- (MRSA) and vancomycin-resistant staphylococci (VRSA) and penicillin-resistant streptococci with a MIC90 value of 2 μg/mL for MRSA. Ceftobiprole also inhibits gram-positive and gram-negative pathogens[1][2][3].
Web ID
– HY-112579
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C20H22N8O6S2
References
– [1]Kisgen J, et al. Ceftobiprole, a Broad-Spectrum Cephalosporin With Activity against Methicillin-Resistant <i>Staphylococcus aureus</i> (MRSA). P T. 2008 Nov;33(11):631-41.|[2]Hodille E, et al. In vitro activity of ceftobiprole on 440 <i>Staphylococcus aureus</i> strains isolated from bronchopulmonary infections. Med Mal Infect. 2017 Mar;47(2):152-157.|[3]E Azoulay-Dupuis, et al. Efficacy of BAL5788, a prodrug of cephalosporin BAL9141, in a mouse model of acute pneumococcal pneumonia. Antimicrob Agents Chemother. 2004 Apr;48(4):1105-11.
CAS Number
– 209467-52-7
Molecular Weight
– 534.57
Compound Purity
– 95.0
SMILES
– O=C(C(N12)=C(/C=C3C(N([C@H]4CNCC4)CC/3)=O)CS[C@]2([H])[C@H](NC(/C(C5=NSC(N)=N5)=NO)=O)C1=O)O
Clinical Information
– Launched
Research Area
– Infection; Inflammation/Immunology
Solubility
– DMSO : 4.95 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Antibiotic;Bacterial
Isoform
– β-lactam
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
