Products Details

Product Description

– Cefilavancin (TD-1792) is a potent multivalent glycopeptide-cephalosporin heterodimer antibiotic with effective activity against Gram-positive bacteria. Cefilavancin has been used to research skin infections[1][2][3].

Web ID

– HY-19466

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C87H95Cl3N16O28S2

References

– [1]Blais J, et al. Antistaphylococcal activity of TD-1792, a multivalent glycopeptide-cephalosporin antibiotic. Antimicrob Agents Chemother. 2012 Mar;56(3):1584-7.|[2]Stryjewski ME, et al. TD-1792 versus vancomycin for treatment of complicated skin and skin structure infections. Antimicrob Agents Chemother. 2012 Nov;56(11):5476-83.|[3]Hegde SS, et al. Pharmacodynamics of TD-1792, a novel glycopeptide-cephalosporin heterodimer antibiotic used against Gram-positive bacteria, in a neutropenic murine thigh model. Antimicrob Agents Chemother. 2012 Mar;56(3):1578-83.

CAS Number

– 1393900-12-3

Molecular Weight

– 1983.26

SMILES

– [O-]C(C1=C(C[N+]2=CC=CC=C2)CS[C@@]([C@@H]3NC(/C(C4=C(SC(N)=N4)Cl)=NOCCCNC([C@@H]5C6=CC(O)=CC(O)=C6C7=CC([C@]8([H])C(N[C@]([C@@H](C9=CC=C(OC%10=CC([C@](NC([C@@H](NC([C@@H]([C@@H](C%11=CC=C(O%12)C(Cl)=C%11)O)NC([C@H](NC)CC(C)C)=O)=O)CC(N)=O)=O)([H])C(N8)=O)=CC%12=C%10O[C@H]%13[C@@H]([C@H]([C@@H]([C@H](O%13)CO)O)O)O[C@H]%14C[C@](N)([C@@H]([C@@H](O%14)C)O)C)C(Cl)=C9)O)([H])C(N5)=O)=O)=CC=C7O)=O)=O)([H])N1C3=O)=O

Clinical Information

– No Development Reported

Research Area

– Infection

Solubility

– 10 mM in DMSO

Target

– Antibiotic;Bacterial

Isoform

– Glycopeptide

Pathway

– Anti-infection

Product type

– Peptides

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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