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Cefaloglycin
Products Details
Product Description
– Cefaloglycin (Cephaloglycin) is an orally active nephrotoxic β-lactam cephalosporin antibiotic with antibacterial activity. Cefaloglycin is activity against Gram-Positive cocci other than enterococci. Cefaloglycin is toxic to mitochondrial substrate uptake and respiration[1][2][3].
Web ID
– HY-16137
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C18H19N3O6S
References
– [1]B M Tune, et al. The Renal Mitochondrial Toxicity of Beta-Lactam Antibiotics: In Vitro Effects of Cephaloglycin and Imipenem. J Am Soc Nephrol. 1990 Nov;1(5):815-21.|[2]S Shadomy, et al. In Vitro Activities of Five Oral Cephalosporins Against Aerobic Pathogenic Bacteria. Antimicrob Agents Chemother. 1977 Nov;12(5):609-13.|[3]E Bergogne-Bérézin. Continuous Activity of Significant Antibiotics. Clin Ther. Jan-Feb 1991;13(1):181-8.
CAS Number
– 3577-01-3
Molecular Weight
– 405.42
SMILES
– OC(C(N(C1=O)[C@@](SC2)([H])[C@@H]1NC([C@@H](C3=CC=CC=C3)N)=O)=C2COC(C)=O)=O
Clinical Information
– Launched
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
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