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Cedrol
$25 – $28
Products Details
Product Description
– Cedrol is a bioactive sesquiterpene, a potent competitive inhibitor of cytochrome P-450 (CYP) enzymes. Cedrol inhibits CYP2B6-mediated bupropion hydroxylase and CYP3A4-mediated midazolam hydroxylation with Ki of 0.9 μM and 3.4 μM, respectively. Cedrol also has weak inhibitory effect on CYP2C8, CYP2C9, and CYP2C19 enzymes[1]. Cedrol is found in cedar essential oil and poetesses anti-septic, anti-inflammatory, anti-spasmodic, tonic, astringent, diuretic, insecticidal, and anti-fungal activities[2].
Web ID
– HY-N2071
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C15H26O
References
– [1]Jeong HU, et al. Inhibitory effects of cedrol, β-cedrene, and thujopsene on cytochrome P450 enzyme activities in human liver microsomes. J Toxicol Environ Health A. 2014;77(22-24):1522-32.|[2]Jin MH, et al. Cedrol Enhances Extracellular Matrix Production in Dermal Fibroblasts in a MAPK-Dependent Manner. Ann Dermatol. 2012 Feb;24(1):16-21
CAS Number
– 77-53-2
Molecular Weight
– 222.37
Compound Purity
– 98.0
SMILES
– O[C@]1(C)CC[C@]23[C@H](C)CC[C@@]2([H])C(C)(C)[C@@]1([H])C3
Clinical Information
– No Development Reported
Research Area
– Infection; Inflammation/Immunology; Cancer
Solubility
– DMSO : 110 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL
Target
– Cytochrome P450;Fungal
Isoform
– CYP2;CYP3
Pathway
– Anti-infection;Metabolic Enzyme/Protease
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
