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Products Details
Product Description
– CDK9-IN-29 (compound Z11) is a potent CDK9 inhibitor (IC50 = 3.20 nM) with good kinase selectivity. CDK9-IN-29 inhibits cell proliferation and induces apoptosis[1].
Web ID
– HY-149641
Shipping
– Room temperature
Molecular Formula
– C29H33F2N5O4
References
– [1]Tizhi Wu, et al. Discovery of Selective and Potent Macrocyclic CDK9 Inhibitors for the Treatment of Osimertinib-Resistant Non-Small-Cell Lung Cancer. J Med Chem. 2023.
CAS Number
– 2737262-24-5
Molecular Weight
– 553.60
SMILES
– FC1=C(C=C(C=C1)C2=C(C=NC(N3)=N2)F)OCCCCCCOC4=CC3=CC=C4C(NCCN5CCOCC5)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– CDK
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
