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Products Details
Product Description
– CDK9-IN-12 displays the optimal CDK9 inhibitory activity with an IC50 value of 5.41 nM.
Web ID
– HY-115714
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C21H19ClN4O
References
– [1]Han X, et al. Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia. J Med Chem. 2021 Oct 14;64(19):14647-14663.
CAS Number
– 1942843-54-0
Molecular Weight
– 378.85
SMILES
– ClC1=C(C=C(C=N1)N[C@@H](CO)C2=CC=CC=C2)C3=CC=C(C4=C3)NN=C4C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– CDK
Isoform
– CDK9
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
