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Products Details
Product Description
– CDK7-IN-8 is a potent CDK7 inhibitor with IC50 of 54.29 nM. CDK7-IN-8 has inhibitory effect on certain cancer cells and in vivo tumor models[1].
Web ID
– HY-143586
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C25H38N8O3
References
– [1]Hu Yonghan, et al. Heterocyclic compound, and pharmaceutical composition thereof, preparation method therefor, intermediate thereof and application thereof. WO2021121390
CAS Number
– 2654003-64-0
Molecular Weight
– 498.62
SMILES
– CC(C1=C2N(N=C1)C(NC3CCN(CC3)C(O[C@@H]4CN(CC4)C(/C=C/CN(C)C)=O)=O)=NC(C)=N2)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– CDK
Isoform
– CDK7
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
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