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Products Details
Product Description
– CDK7-IN-2 hydrochloride hydrate (Example 6) is a potent and selective CDK7 inhibitor. CDK7-IN-2 has potent anti-cancer activity[1][2].
Web ID
– HY-136711
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C26H42ClN7O4
References
– [1]Georgina P Sava, et al. CDK7 inhibitors as anticancer drugs. Cancer Metastasis Rev. 2020 May 8.|[2]David Andrew Coates, et al. (e)-1-(4-(dimethylamino)but-2-enoyl)pyrrolidin-3-yl 4-((3-isopropyl-5-methylpyrazolo[1,5-a]pyrimidin-7-yl)amino)piperidine-1-carboxylate for inhibiting cdk7, US20200017513A1.
CAS Number
– 2326428-24-2
Molecular Weight
– 552.11
SMILES
– O=C(N1CCC(NC2=CC(C)=NC3=C(C(C)C)C=NN23)CC1)O[C@@H]4CN(C(/C=C/CN(C)C)=O)CC4.O.Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– CDK
Isoform
– CDK7
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
