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Products Details
Product Description
– CDK4/6-IN-7 is a potent, selective and orally active CDK4/6 inhibitor, with IC50s of 1.58 and 4.09 nM, respectively. CDK4/6-IN-7 can be used for the research of breast cancer[1].
Web ID
– HY-143257
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C18H18ClN5O3
References
– [1]Liang JW, et, al. Synthesis and identification of a novel skeleton of N-(pyridin-3-yl) proline as a selective CDK4/6 inhibitor with anti-breast cancer activities. Bioorg Chem. 2022 Feb;119:105547.
CAS Number
– 2649120-20-5
Molecular Weight
– 387.82
SMILES
– O=C(C1=CC=CC=C1Cl)NNC(N2CCC[C@@H]2C(NC3=CC=CN=C3)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– CDK
Isoform
– CDK4;CDK6
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
