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Products Details
Product Description
– CDK4/6-IN-5 is a potent CDK4 and CDK6 inhibitor with Kis of 0.2 and 4.4 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3, respectively[1]. (from patent WO2019207463A1 example A93).
Web ID
– HY-139449
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C22H28ClFN6O4S
References
– [1]Ping Chen, et al. 2-amino-pyridine or 2-amino-pyrimidine derivatives as cyclin dependent kinase inhibitors. WO2019207463A1.
CAS Number
– 2380321-50-4
Molecular Weight
– 527.01
SMILES
– CC(N1C2=CC(C3=NC(N[C@H]4[C@@H](CN(CC4)S(C)(=O)=O)O)=NC=C3Cl)=CC(F)=C2N=C1[C@H](O)C)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– CDK
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
