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Products Details
Product Description
– CDK4/6-IN-17 (Compound 12) is a CDK4/6 inhibitor (IC50: <5 μM). CDK4/6-IN-17 inhibits BE(2)-C cell proliferation (IC50: 10-100 nM) . CDK4/6-IN-17 inhibits tumor growth in COLO205 xenograft tumors[1].
Web ID
– HY-153704
Shipping
– Room temperature
Molecular Formula
– C27H28F4N8
References
– [1]Zhao Xingdong. A kind of kinase inhibitor. Patent. CN107849012.|[2]Zhao X, et al. Preparation of benzopyrroloimidazolyl compounds as CDK4/6 kinase inhibitors. World Intellectual Property Organization, WO2016173505 A1. 2016-11-03.
CAS Number
– 2035069-96-4
Molecular Weight
– 540.56
SMILES
– FC([C@H]1N2C3=CC(C4=NC(NC5=CC=C(C=N5)CN6CCN(CC6)CC)=NC=C4F)=CC(F)=C3N=C2CC1)F
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– CDK
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
