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Product Description
– CDK2-IN-8 is a potent CDK2 inhibitor with an IC50 of 1.74 µM. CDK2-IN-8 shows antiproliferative activity. CDK2-IN-8 has the potential for the research of melanoma[1].
Web ID
– HY-144810
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C22H25N5O3
References
– [1]Mohammed ER, et al. Development of newly synthesised quinazolinone-based CDK2 inhibitors with potent efficacy against melanoma. J Enzyme Inhib Med Chem. 2022 Dec;37(1):686-700.
CAS Number
– 2919216-36-5
Molecular Weight
– 407.47
SMILES
– O=C(NN1C(COC2=CC=CC=C2)=NC3=C(C=CC=C3)C1=O)CN4CCN(C)CC4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– CDK
Isoform
– CDK2
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
